IKZF3 Polyclonal Antibody | G-AB-11605

IKZF3 Polyclonal Antibody | G-AB-11605 | Gentaur Antibodies

Overview: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: IKZF3, AIO, AIOLOS, ZNFN1A3

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 22806

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IKZF3 (NP_036613.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UKT9

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IKZF3 Polyclonal Antibody DataSheet