IL1 beta Polyclonal Antibody | G-AB-07486
Gentaur Antibodies
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Gentaur Antibodies
IL1 beta Polyclonal Antibody | G-AB-07486
- SKU:
- G-AB-07486
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
IL1 beta Polyclonal Antibody | G-AB-07486 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Immunology
Synonyms: IL-1, IL1-BETA, IL1F2, IL1 beta, IL1B
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 3553
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human IL1 beta (NP_000567.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P01584
Santa Cruz:
Calculated MW: 30 kDa
Observed MW: 31 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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