IL1 beta Polyclonal Antibody | G-AB-09368

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$218.00 - $465.00
SKU:
G-AB-09368
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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IL1 beta Polyclonal Antibody | G-AB-09368 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Immunology

Synonyms: IL-1, IL1-BETA, IL1F2, IL1 beta, IL1B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3553

Accession #:

Clonality:

Immunogen: A synthetic peptide of human IL1 beta

Clone #:

Conjugation: Unconjugated

Swissprot: P01584

Santa Cruz:

Calculated MW: 30 kDa

Observed MW: 17 kDa/31 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL1 beta Polyclonal Antibody DataSheet

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