IL10 Polyclonal Antibody | G-AB-09990

IL10 Polyclonal Antibody | G-AB-09990 | Gentaur Antibodies

Overview: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: CSIF, GVHDS, IL-10, IL10A, TGIF, IL10

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3586

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IL10 (NP_000563.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P22301

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL10 Polyclonal Antibody DataSheet