IRF4 Polyclonal Antibody | G-AB-07410

IRF4 Polyclonal Antibody | G-AB-07410 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t (6;14) (p25;q32) , may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Tags & Cell Markers

Synonyms: IRF4, LSIRF, MUM1, NF-EM5, SHEP8, IRF-4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 3662

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IRF4 (NP_002451.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q15306

Santa Cruz:

Calculated MW: 51 kDa

Observed MW: 52 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IRF4 Polyclonal Antibody DataSheet