JNK1/2 Polyclonal Antibody | G-AB-09772

JNK1/2 Polyclonal Antibody | G-AB-09772 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported./The protein encoded by this gene is a member of the MAP kinase family.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: JNK1/2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5599/5601

Accession #:

Clonality:

Immunogen: Recombinant protein of human JNK1/2.

Clone #:

Conjugation: Unconjugated

Swissprot: P45983, P45984

Santa Cruz:

Calculated MW: 48 kDa

Observed MW: 45 kDa/60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

JNK1/2 Polyclonal Antibody DataSheet