JNK1 Polyclonal Antibody | G-AB-01322

JNK1 Polyclonal Antibody | G-AB-01322 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Signal Transduction

Synonyms: AI849689, c Jun N terminal kinase 1, C-JUN kinase 1, c-Jun N-terminal kinase 1, EC 2.7.11.24, JNK 1, JNK, JNK-46, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, mapk8, Mitogen activated protein kinase 8, Mitogen-activated protein kinase 8, MK08, p54 gamma, Prkm8, Protein kinase JNK1, Protein kinase, mitogen-activated, 8, SAPK 1, SAPK gamma, SAPK1, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_620637

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MAPK8

Clone #:

Conjugation: Unconjugated

Swissprot: P45983

Santa Cruz: sc-46006/sc-46009/sc-46007/sc-46008/sc-571/sc-474

Calculated MW: 48 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

JNK1 Polyclonal Antibody DataSheet