JPT1 Polyclonal Antibody | G-AB-06546

JPT1 Polyclonal Antibody | G-AB-06546 | Gentaur Antibodies

Overview: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408) . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422) . Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365) . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408) .

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: Androgen regulated protein 2, Androgen-regulated protein 2, ARM2, Hematological and neurological expressed 1, Hematological and neurological expressed 1 protein, HN1, HN1, HN1A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC001420

Clonality: Polyclonal

Immunogen: Fusion protein of human JPT1

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UK76

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

JPT1 Polyclonal Antibody DataSheet