KCNA1 Polyclonal Antibody | G-AB-02791

KCNA1 Polyclonal Antibody | G-AB-02791 | Gentaur Antibodies

Overview: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6) , and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD) . The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: AEMK, EA1, Episodic ataxia with myokymia, HBK1, HUK1, Kca1 1, Kcna1, KCNA1, Kcpvd, KV1.1, MBK1, mceph, MGC124402, MGC126782, MGC138385, MK1, MK1, mouse, homolog of KV1.1, Potassium channel protein 1, Potassium voltage gated channel shaker related subfamily member 1, Potassium voltage gated channel subfamily A member 1, Potassium voltage gated channel, shaker related subfamily, member 1 (episodic ataxia with myokymia) , Potassium voltage-gated channel subfamily A member 1, RBK1, RCK1, Shak, Shaker related subfamily member 1, Voltage gated potassium channel subunit Kv1.1, Voltage-gated K (+) channel HuKI, Voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv1.1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000208

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KCNA1

Clone #:

Conjugation: Unconjugated

Swissprot: Q09470

Santa Cruz: sc-11184/sc-11182/sc-25680

Calculated MW: 56 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:15-1:50

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KCNA1 Polyclonal Antibody DataSheet