KCNA1 Polyclonal Antibody | G-AB-10241

KCNA1 Polyclonal Antibody | G-AB-10241 | Gentaur Antibodies

Overview: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6) , and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD) . The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: KCNA1, AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3736

Accession #:

Clonality:

Immunogen: A synthetic peptide of human KCNA1

Clone #:

Conjugation: Unconjugated

Swissprot: Q09470

Santa Cruz:

Calculated MW: 56 kDa

Observed MW: 56 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KCNA1 Polyclonal Antibody DataSheet