KDM5B Polyclonal Antibody | G-AB-01753

KDM5B Polyclonal Antibody | G-AB-01753 | Gentaur Antibodies

Overview: PLU-1 is a large (1, 544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9) , both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, JARID1B, Jumonji AT rich interactive domain 1B, Jumonji/ARID domain-containing protein 1B, Kdm5b, KDM5B, Lysine (K) specific demethylase 5B, Lysine demethylase 5B, Lysine specific demethylase 5B, Lysine-specific demethylase 5B, PLU-1, PLU1, PPP1R98, Protein phosphatase 1 regulatory subunit 98, PUT1, putative DNA/chromatin binding motif, RBBP2H1A, RBP2 like, RBP2-H1, Retinoblastoma-binding protein 2 homolog 1, Retinoblastoma-binding protein 2 homolog 1A

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006609

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KDM5B

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UGL1

Santa Cruz: sc-31612/sc-31613/sc-67035

Calculated MW:

Observed MW:

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KDM5B Polyclonal Antibody DataSheet