KIF3A Polyclonal Antibody | G-AB-11224

KIF3A Polyclonal Antibody | G-AB-11224 | Gentaur Antibodies

Overview: Kinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction, Stem Cells

Synonyms: KIF3A, FLA10, KLP-20

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 11127

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human KIF3A (NP_008985.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y496

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KIF3A Polyclonal Antibody DataSheet