KLC1 Polyclonal Antibody | G-AB-02286

KLC1 Polyclonal Antibody | G-AB-02286 | Gentaur Antibodies

Overview: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: Kinesin 2 60/70kDa, Kinesin light chain 1, Kinesin2, KLC 1, KLC, Klc1, KLC1, KNS 2, KNS 2A, KNS2, KNS2A, Medulloblastoma antigen MU MB 2.50, MGC15245

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC008881

Clonality: Polyclonal

Immunogen: Recombinant protein of human KLC1

Clone #:

Conjugation: Unconjugated

Swissprot: Q07866

Santa Cruz: sc-13361/sc-13362/sc-25735

Calculated MW: 65 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KLC1 Polyclonal Antibody DataSheet