KLRC1 Polyclonal Antibody | G-AB-07760

KLRC1 Polyclonal Antibody | G-AB-07760 | Gentaur Antibodies

Overview: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: KLRC1, CD159A, NKG2, NKG2A

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 3821

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human KLRC1 (NP_015567.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P26715

Santa Cruz:

Calculated MW: 24 kDa/26 kDa

Observed MW: 26 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KLRC1 Polyclonal Antibody DataSheet