(KO Validated) APEX1 Polyclonal Antibody | G-AB-10147
- 3 to 5 Working Days
(KO Validated) APEX1 Polyclonal Antibody | G-AB-10147 | Gentaur Antibodies
Overview: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling
Synonyms: APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1
Gene ID: 328
Immunogen: Recombinant fusion protein of human APEX1 (NP_542380.1) .
Calculated MW: 35 kDa
Observed MW: 39 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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I ordered the Polyclonal antibody APEX-1 and as my expectations were the product was of very fine higher quality so glad to my satisfaction.