(KO Validated) HSPB1 Polyclonal Antibody | G-AB-09377

(KO Validated) HSPB1 Polyclonal Antibody | G-AB-09377 | Gentaur Antibodies

Overview: This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: HSPB1, CMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3315

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HSPB1 (NP_001531.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P04792

Santa Cruz:

Calculated MW: 23 kDa

Observed MW: 25 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

(KO Validated) HSPB1 Polyclonal Antibody DataSheet