(KO Validated) HuR / ELAVL1 Polyclonal Antibody | G-AB-10934
- 3 to 5 Working Days
- Human, Mouse
(KO Validated) HuR / ELAVL1 Polyclonal Antibody | G-AB-10934 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: ELAV1, HUR, Hua, MelG, HuR / ELAVL1, ELAVL1
Reactivity: Human, Mouse
Gene ID: 1994
Immunogen: A synthetic peptide of human HuR / ELAVL1 (NP_001410.2) .
Calculated MW: 36 kDa/38 kDa
Observed MW: 36 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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