KPNB1 Polyclonal Antibody | G-AB-01734

KPNB1 Polyclonal Antibody | G-AB-01734 | Gentaur Antibodies

Overview: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Tags & Cell Markers

Synonyms: IMB 1, IMB1, IMB1, Impnb, Importin 90, Importin beta 1, Importin beta 1 subunit, Importin subunit beta-1, Importin-90, IPOB, Karyopherin beta 1, Karyopherin beta 1 subunit, Karyopherin subunit beta-1, KPNB 1, Kpnb1, MGC2155, MGC2156, MGC2157, NTF 97, NTF97, Nuclear factor P97, Pore targeting complex 97 kDa subunit, PTAC97

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002256

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KPNB1

Clone #:

Conjugation: Unconjugated

Swissprot: Q14974

Santa Cruz: sc-1863/sc-1919/sc-11367

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KPNB1 Polyclonal Antibody DataSheet