KU70 Polyclonal Antibody | G-AB-11634

KU70 Polyclonal Antibody | G-AB-11634 | Gentaur Antibodies

Overview: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2547

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human KU70 (NP_001460.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P12956

Santa Cruz:

Calculated MW: 65 kDa/69 kDa

Observed MW: 70 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KU70 Polyclonal Antibody DataSheet