L1CAM Polyclonal Antibody | G-AB-12680

L1CAM Polyclonal Antibody | G-AB-12680 | Gentaur Antibodies

Overview: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III) , is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction, Neuroscience

Synonyms: Antigen identified by monoclonal antibody R1, CAML1, CD171, CD171 antigen, HSAS, HSAS1, Hyd, L1 cell adhesion molecule, L1, MASA, L1cam, MIC5, NCAML1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, OTTHUMP00000025992, S10, SPG1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3897

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Neural cell adhesion molecule L1 protein

Clone #:

Conjugation: Unconjugated

Swissprot: P32004

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification method: Antigen Affinity Purification

Application: IHC

Dilution: IHC 1:100-1:300

Storage: Store at -20℃. Avoid freeze / thaw cycles.

L1CAM Polyclonal Antibody DataSheet