L1CAM Polyclonal Antibody | G-AB-12681
- 3 to 5 Working Days
- Mouse, Rat
L1CAM Polyclonal Antibody | G-AB-12681 | Gentaur Antibodies
Overview: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III) , is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction, Neuroscience
Synonyms: Antigen identified by monoclonal antibody R1, CAML1, CD171, CD171 antigen, HSAS, HSAS1, Hyd, L1 cell adhesion molecule, L1, MASA, L1cam, MIC5, NCAML1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, OTTHUMP00000025992, S10, SPG1
Reactivity: Mouse, Rat
Gene ID: 16728
Immunogen: Recombinant Mouse Neural cell adhesion molecule L1 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Dilution: IHC 1:200-1:500
Storage: Store at -20℃. Avoid freeze / thaw cycles.