LECT1 Polyclonal Antibody | G-AB-11229

LECT1 Polyclonal Antibody | G-AB-11229 | Gentaur Antibodies

Overview: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: CNMD, BRICD3, CHM-I, CHM1, LECT1, MYETS1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 11061

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LECT1 (NP_008946.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75829

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LECT1 Polyclonal Antibody DataSheet