LILRB2 Polyclonal Antibody | G-AB-07714

LILRB2 Polyclonal Antibody | G-AB-07714 | Gentaur Antibodies

Overview: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Immunology

Synonyms: LILRB2, CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10288

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LILRB2 (NP_005865.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q8N423

Santa Cruz:

Calculated MW: 51 kDa/55 kDa/64 kDa/65 kDa

Observed MW: 65 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LILRB2 Polyclonal Antibody DataSheet