LIMK1 Polyclonal Antibody | G-AB-01762

LIMK1 Polyclonal Antibody | G-AB-01762 | Gentaur Antibodies

Overview: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Synonyms: EC 2.7.1.37, LIM domain containing protein kinase, LIM domain kinase 1, LIM kinase, LIM motif containing protein kinase, LIMK 1, LIMK, LIMK-1, limk1, LIMK1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002305

Clonality: Polyclonal

Immunogen: Synthetic peptide of human LIMK1

Clone #:

Conjugation: Unconjugated

Swissprot: P53667

Santa Cruz: sc-30698/sc-30696/sc-30696/sc-8387/sc-5576

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LIMK1 Polyclonal Antibody DataSheet