LOXL1 Polyclonal Antibody | G-AB-07330

LOXL1 Polyclonal Antibody | G-AB-07330 | Gentaur Antibodies

Overview: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Category Type: Polyclonal Antibody

Research Areas: Cell biology, Metabolism, Signal Transduction

Synonyms: LOXL1, LOL, LOXL

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4016

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LOXL1 (NP_005567.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q08397

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LOXL1 Polyclonal Antibody DataSheet