LUM Polyclonal Antibody | G-AB-00018

LUM Polyclonal Antibody | G-AB-00018 | Gentaur Antibodies

Overview: Lumican (LUM) , a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Studies show that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Keratan sulfate proteoglycan lumican, KSPG lumican, LDC, LUM, LUM, Lumican, Lumican precursor, SLRR2D

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Lumican protein

Clone #:

Conjugation: Unconjugated

Swissprot: P51884

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 2 mg/mL

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LUM Polyclonal Antibody DataSheet