LXR alpha Polyclonal Antibody | G-AB-09966

LXR alpha Polyclonal Antibody | G-AB-09966 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR) , and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms: NR1H3, LXR-a, LXRA, RLD-1, LXR alpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10062

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LXR alpha (NP_005684.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13133

Santa Cruz:

Calculated MW: 43 kDa/45 kDa/50 kDa

Observed MW: 50 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LXR alpha Polyclonal Antibody DataSheet