MAPKBP1 Polyclonal Antibody | G-AB-10160
Gentaur Antibodies
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Gentaur Antibodies
MAPKBP1 Polyclonal Antibody | G-AB-10160
- SKU:
- G-AB-10160
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
MAPKBP1 Polyclonal Antibody | G-AB-10160 | Gentaur Antibodies
Overview: This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: MAPKBP1, JNKBP-1, JNKBP1, NPHP20
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 23005
Accession #:
Clonality:
Immunogen: A synthetic peptide of human MAPKBP1 (NP_001122080.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O60336
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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