MCM2 Polyclonal Antibody | G-AB-07420

MCM2 Polyclonal Antibody | G-AB-07420 | Gentaur Antibodies

Overview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: MCM2, BM28, CCNL1, CDCL1, D3S3194, DFNA70, MITOTIN, cdc19

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4171

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MCM2 (NP_004517.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49736

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MCM2 Polyclonal Antibody DataSheet