MCM6 Polyclonal Antibody | G-AB-00581

MCM6 Polyclonal Antibody | G-AB-00581 | Gentaur Antibodies

Overview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) , MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC032374

Clonality: Polyclonal

Immunogen: Recombinant protein of human MCM6

Clone #:

Conjugation: Unconjugated

Swissprot: Q14566

Santa Cruz: sc-9843/sc-9845/sc-22781

Calculated MW: 93 kDa

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MCM6 Polyclonal Antibody DataSheet