MCM6 Polyclonal Antibody | G-AB-02067
Gentaur Antibodies
- SKU:
- G-AB-02067
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
MCM6 Polyclonal Antibody | G-AB-02067 | Gentaur Antibodies
Overview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) , MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC032374
Clonality: Polyclonal
Immunogen: Recombinant protein of human MCM6
Clone #:
Conjugation: Unconjugated
Swissprot: Q14566
Santa Cruz: sc-9843/sc-9845/sc-22781
Calculated MW: 93 kDa
Observed MW:
Concentration: 0.8 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:100-1:300
Storage: Store at -20°C. Avoid freeze / thaw cycles.