MDC1 Polyclonal Antibody | G-AB-12158
Gentaur Antibodies
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Gentaur Antibodies
MDC1 Polyclonal Antibody | G-AB-12158
- SKU:
- G-AB-12158
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
MDC1 Polyclonal Antibody | G-AB-12158 | Gentaur Antibodies
Overview: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: MDC1, NFBD1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 9656
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human MDC1 (NP_055456.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q14676
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:100-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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