MDH1 Polyclonal Antibody | G-AB-11754

MDH1 Polyclonal Antibody | G-AB-11754 | Gentaur Antibodies

Overview: This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: MDH1, HEL-S-32, MDH-s, MDHA, MGC:1375, MOR2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4190

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MDH1 (NP_005908.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P40925

Santa Cruz:

Calculated MW: 27 kDa/36 kDa/38 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MDH1 Polyclonal Antibody DataSheet