METTL7A Polyclonal Antibody | G-AB-12089

METTL7A Polyclonal Antibody | G-AB-12089 | Gentaur Antibodies

Overview: METTL7A (methyltransferase like 7A) , also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1, 100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: METTL7A, AAM-B

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 25840

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human METTL7A (NP_054752.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H8H3

Santa Cruz:

Calculated MW: 28 kDa

Observed MW: 28 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

METTL7A Polyclonal Antibody DataSheet