MLH3 Polyclonal Antibody | G-AB-11874

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$218.00 - $465.00
SKU:
G-AB-11874
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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MLH3 Polyclonal Antibody | G-AB-11874 | Gentaur Antibodies

Overview: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: MLH3, HNPCC7

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 27030

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MLH3 (NP_055196.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UHC1

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MLH3 Polyclonal Antibody DataSheet