MLPH Polyclonal Antibody | G-AB-11233

MLPH Polyclonal Antibody | G-AB-11233 | Gentaur Antibodies

Overview: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: MLPH, SLAC2-A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 79083

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MLPH (NP_077006.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BV36

Santa Cruz:

Calculated MW: 50 kDa/52 kDa/60 kDa/62 kDa/65 kDa

Observed MW: 75 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MLPH Polyclonal Antibody DataSheet