MMP12 Polyclonal Antibody | G-AB-09642

MMP12 Polyclonal Antibody | G-AB-09642 | Gentaur Antibodies

Overview: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD) . This gene is part of a cluster of MMP genes on chromosome 11.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: MMP12, HME, ME, MME, MMP-12

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4321

Accession #:

Clonality:

Immunogen: A synthetic peptide of human MMP12

Clone #:

Conjugation: Unconjugated

Swissprot: P39900

Santa Cruz:

Calculated MW: 54 kDa

Observed MW: 51 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP12 Polyclonal Antibody DataSheet