MMP13 Polyclonal Antibody | G-AB-07623

MMP13 Polyclonal Antibody | G-AB-07623 | Gentaur Antibodies

Overview: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: MMP13, CLG3, MANDP1, MDST, MMP-13

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4322

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MMP13 (NP_002418.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P45452

Santa Cruz:

Calculated MW: 53 kDa

Observed MW: 72 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP13 Polyclonal Antibody DataSheet