MMP2 Monoclonal Antibody | G-AB-05714
- 3 to 5 Working Days
- Human, Mouse, Rat
MMP2 Monoclonal Antibody | G-AB-05714 | Gentaur Antibodies
Overview: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism
Synonyms: 72 kDa gelatinase, 72kD type IV collagenase, CLG 4, CLG 4A, CLG4, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase, Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) , Matrix Metalloproteinase 2, Matrix metalloproteinase II, Matrix metalloproteinase-2, MMP 2, MMP II, MMP-2, MMP2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE 1, TBE-1
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic Peptide of MMP2
Clone #: Clone:1H1
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Protein A purification
Dilution: IHC 1:100-200
Storage: Store at -20°C. Avoid freeze / thaw cycles.