MMP20 Polyclonal Antibody | G-AB-01775

MMP20 Polyclonal Antibody | G-AB-01775 | Gentaur Antibodies

Overview: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: AI2A2, Enamel metalloproteinase, Enamelysin, Matrix metalloproteinase 20, Matrix metalloproteinase-20, MMP 20, MMP-20, MMP20, MMP20

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_004762

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MMP20

Clone #:

Conjugation: Unconjugated

Swissprot: O60882

Santa Cruz: sc-26926

Calculated MW: 54 kDa

Observed MW:

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP20 Polyclonal Antibody DataSheet