MMP7 Polyclonal Antibody | G-AB-07219

MMP7 Polyclonal Antibody | G-AB-07219 | Gentaur Antibodies

Overview: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: MMP7, MMP-7, MPSL1, PUMP-1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4316

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MMP7 (NP_002414.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P09237

Santa Cruz:

Calculated MW: 29 kDa

Observed MW: 26 kDa/34 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP7 Polyclonal Antibody DataSheet