MMP8 Polyclonal Antibody | G-AB-02809

MMP8 Polyclonal Antibody | G-AB-02809 | Gentaur Antibodies

Overview: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: CLG 1, CLG1, Collagenase 1, Collagenase 1 neutrophil, HNC, Matrix metallopeptidase 8 (neutrophil collagenase) , Matrix metalloprotease 8, Matrix metalloproteinase-8, MMP 8, MMP-8, Mmp8, MMP8, Neutrophil collagenase, PMNL CL, PMNL collagenase, PMNL-CL, PMNLCL

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002415

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MMP8

Clone #:

Conjugation: Unconjugated

Swissprot: P22894

Santa Cruz: sc-8849/sc-8848/sc-31741/sc-50383

Calculated MW: 53 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP8 Polyclonal Antibody DataSheet