MRPS31 Polyclonal Antibody | G-AB-07977

MRPS31 Polyclonal Antibody | G-AB-07977 | Gentaur Antibodies

Overview: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Metabolism, Immunology

Synonyms: MRPS31, IMOGN38, MRP-S31, S31mt

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10240

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MRPS31 (NP_005821.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q92665

Santa Cruz:

Calculated MW: 45 kDa

Observed MW: 37 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MRPS31 Polyclonal Antibody DataSheet