MT-ND1 Polyclonal Antibody | G-AB-01779

MT-ND1 Polyclonal Antibody | G-AB-01779 | Gentaur Antibodies

Overview: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7) , while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: Complex I, subunit ND1, Mitochondrially encoded NADH dehydrogenase 1, MT-ND1, MTND1, NAD1, NADH dehydrogenase subunit 1 (complex I) , NADH dehydrogenase subunit 1, NADH-ubiquinone oxidoreductase chain 1, NADH-ubiquinone oxidoreductase, subunit ND1, NADH1, ND1, NU1M

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: YP_003024026

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MT-ND1

Clone #:

Conjugation: Unconjugated

Swissprot: P03886

Santa Cruz:

Calculated MW: 36 kDa

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MT-ND1 Polyclonal Antibody DataSheet