MTHFD1 Polyclonal Antibody | G-AB-12302
- 3 to 5 Working Days
- Human, Mouse, Rat
MTHFD1 Polyclonal Antibody | G-AB-12302 | Gentaur Antibodies
Overview: This gene encodes a protein that possesses three distinct enzymatic activities, 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction
Synonyms: MTHFD1, MTHFC, MTHFD
Reactivity: Human, Mouse, Rat
Gene ID: 4522
Immunogen: Recombinant fusion protein of human MTHFD1 (NP_005947.3) .
Calculated MW: 101 kDa
Observed MW: 115 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:200-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.