MTHFD1 Polyclonal Antibody | G-AB-12302

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$218.00 - $465.00
SKU:
G-AB-12302
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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MTHFD1 Polyclonal Antibody | G-AB-12302 | Gentaur Antibodies

Overview: This gene encodes a protein that possesses three distinct enzymatic activities, 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms: MTHFD1, MTHFC, MTHFD

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4522

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MTHFD1 (NP_005947.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P11586

Santa Cruz:

Calculated MW: 101 kDa

Observed MW: 115 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:200-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MTHFD1 Polyclonal Antibody DataSheet