MTOR Polyclonal Antibody | G-AB-05440

MTOR Polyclonal Antibody | G-AB-05440 | Gentaur Antibodies

Overview: MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. The antibody is specific to MTOR.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1) , FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506 binding protein 12 rapamycin complex associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12 rapamycin complex associated protein, FKBP12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FLJ44809, FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, Mechanistic target of rapamycin, mTOR, MTOR, OTTHUMP00000001983, RAFT1, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein 1, Rapamycin target protein, RAPT1, Serine/threonine-protein kinase mTOR

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant protein corresponding to Mouse mTOR

Clone #:

Conjugation: Unconjugated

Swissprot: P42345, Q9JLN9, P42346

Santa Cruz:

Calculated MW: 289 kDa

Observed MW: 289 kDa

Concentration: 0.8 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MTOR Polyclonal Antibody DataSheet

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