MXI1 Polyclonal Antibody | G-AB-11236

MXI1 Polyclonal Antibody | G-AB-11236 | Gentaur Antibodies

Overview: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: MXI1, MAD2, MXD2, MXI, bHLHc11

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4601

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MXI1 (NP_569157.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P50539

Santa Cruz:

Calculated MW: 20 kDa/21 kDa/26 kDa/32 kDa

Observed MW: 35 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MXI1 Polyclonal Antibody DataSheet