NECTIN1 Polyclonal Antibody | G-AB-02737
Gentaur Antibodies
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Gentaur Antibodies
NECTIN1 Polyclonal Antibody | G-AB-02737
- SKU:
- G-AB-02737
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
NECTIN1 Polyclonal Antibody | G-AB-02737 | Gentaur Antibodies
Overview: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium (2+) -independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms) , and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2) , and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P) . Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Microbiology, Neuroscience
Synonyms: CD111, CD111 antigen, CLPED1, ectodermal dysplasia 4 (Margarita Island type) , ED4, Herpes virus entry mediator C, Herpesvirus entry mediator C, Herpesvirus Ig like receptor, Herpesvirus Ig-like receptor, HIgR, HveC, MGC142031, Nectin 1, Nectin-1, OFC7, OROFACIAL CLEFT 7, OTTHUMP00000232093, OTTHUMP00000232094, OTTHUMP00000232095, Poliovirus receptor related protein 1, poliovirus receptor-like 1, Poliovirus receptor-related protein 1, PRR, PRR1, PVRL 1, PVRL1, PVRL1, PVRR, PVRR1, SK-12
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_002846
Clonality: Polyclonal
Immunogen: Synthetic peptide of human PVRL1
Clone #:
Conjugation: Unconjugated
Swissprot: Q15223
Santa Cruz:
Calculated MW: 57 kDa
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, ELISA
Dilution: WB 1:200-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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