NEFL Polyclonal Antibody | G-AB-07156

NEFL Polyclonal Antibody | G-AB-07156 | Gentaur Antibodies

Overview: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E) , disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms: NEFL, CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4747

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human NEFL (NP_006149.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P07196

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NEFL Polyclonal Antibody DataSheet