NF2 Polyclonal Antibody | G-AB-10074

NF2 Polyclonal Antibody | G-AB-10074 | Gentaur Antibodies

Overview: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Synonyms: NF2, ACN, BANF, SCH, merlin

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 4771

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human NF2 (NP_000259.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P35240

Santa Cruz:

Calculated MW: 19-30 kDa/59-72 kDa

Observed MW: 70 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NF2 Polyclonal Antibody DataSheet